Julian J. Hsieh
Journal of Vacuum Science and Technology A: Vacuum, Surfaces and Films
Microcontact printing of proteins proves to be an excellent means of directly patterning biomolecules on solid substrates. Monolayer quantities of protein equilibrated on the surface of a hydrophobic, elastomeric stamp are immobilized there to rinses with buffer. These biomolecules can nevertheless transfer with >99% efficiency from the stamp to a substrate after just 1 s of contact. This capability allows the simple creation of functional patterns of proteins at scales that involve the placement of <1000 molecules in well-defined locations on a surface. The method is suited for the transfer of proteins of many different types onto hydrophilic or hydrophobic substrates.
Julian J. Hsieh
Journal of Vacuum Science and Technology A: Vacuum, Surfaces and Films
S. Cohen, T.O. Sedgwick, et al.
MRS Proceedings 1983
Sharee J. McNab, Richard J. Blaikie
Materials Research Society Symposium - Proceedings
Imran Nasim, Melanie Weber
SCML 2024