Nanogel star polymer architectures: A nanoparticle platform for modular programmable macromolecular self-assembly, intercellular transport, and dual-mode cargo delivery

Abstract

Nanogel star polymers are developed as a new route for the formation of dual-mode nanoparticle systems for applications in the areas of synergistic therapeutic delivery, imaged therapeutic delivery, and dual-mode bioimaging agents. These extremely uniform, structurally versatile, water-soluble, unimolecular organic nanoparticles with tunable polyvalency and functionality are preprogrammed to spontaneously upload different types of complex functional macromolecules. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.