Dyadic matrices are natural data representations in a wide range of domains. A dyadic matrix often involves two types of abstract objects and is based on observations of pairs of elements with one element from each object. Owing to the increasing needs from practical applications, dyadic data analysis has recently attracted increasing attention and many techniques have been developed. However, most existing approaches, such as co-clustering and relational reasoning, only handle a single dyadic table and lack flexibility to perform prediction using multiple dyadic matrices. In this article, we propose a general nonparametric Bayesian framework with a cascaded structure to model multiple dyadic matrices and then describe an efficient hybrid Gibbs sampling algorithm for posterior inference and analysis. Empirical evaluations using both synthetic data and real data show that the proposed model captures the hidden structure of data and generalizes the predictive inference in a unique way. © 2012 Copyright Taylor and Francis Group, LLC.