Pin-Yu Chen, Cho-Jui Hsieh, et al.
KDD 2022
Data on genome organization and output over time, or the 4D Nucleome (4DN), require synthesis for meaningful interpretation. Development of tools for the efficient integration of these data is needed, especially for the time dimension. We present the ‘4DNvestigator’, a user-friendly network-based toolbox for the analysis of time series genome-wide genome structure (Hi-C) and gene expression (RNA-seq) data. Additionally, we provide methods to quantify network entropy, tensor entropy, and statistically significant changes in time series Hi-C data at different genomic scales.
Pin-Yu Chen, Cho-Jui Hsieh, et al.
KDD 2022
Gaoyuan Zhang, Songtao Lu, et al.
UAI 2022
Minhao Cheng, Simranjit Singh, et al.
ICLR 2020
Shuai Zhang, Meng Wang, et al.
CISS 2020