Amir Ali Ahmadi, Raphaël M. Jungers, et al.
SICON
Unequal cell division, leading to daughter cells of different sizes, is a common event during development. We have formulated a model that shows how different cell sizes can lead to significant differences in the expression of an activator gene. The model is based on well-known aspects of the regulation of gene expression, specifically the existence of multiple regulatory sites, positive autoregulation, and the short half-life of regulatory proteins. Thus the daughter cells may follow distinct differentiation pathways even if there were no localized determinants in the mother cell. © 1995 Academic Press. All rights reserved.
Amir Ali Ahmadi, Raphaël M. Jungers, et al.
SICON
David W. Jacobs, Daphna Weinshall, et al.
IEEE Transactions on Pattern Analysis and Machine Intelligence
Richard M. Karp, Raymond E. Miller
Journal of Computer and System Sciences
Ruixiong Tian, Zhe Xiang, et al.
Qinghua Daxue Xuebao/Journal of Tsinghua University