Fully autonomous microfluidic capillary systems for fast and sensitive surface immunoassays

Abstract

This paper reports a method for performing fast and sensitive surface immunoassays using fully autonomous microfluidic capillary systems (CSs). A surface immunoassay for C-reactive protein (CRP) having a sensitivity of 0.9 ng mL-1 (30 pM), done in only 10 min and with 1 µL of human serum sample exemplifies the power of CSs.