About cookies on this site Our websites require some cookies to function properly (required). In addition, other cookies may be used with your consent to analyze site usage, improve the user experience and for advertising. For more information, please review your options. By visiting our website, you agree to our processing of information as described in IBM’sprivacy statement. To provide a smooth navigation, your cookie preferences will be shared across the IBM web domains listed here.
Publication
INTERMAG 2003
Conference paper
Design and fabrication of bio-magnetic sensors and magnetic nanobead labels for DNA detection and identification
Abstract
In this paper, the main challenges in developing a magnetic DNA microarray include: 1) The spin valve sensors must be sensitive to as few as 1-10 nanobeads to be useful for applications such as biological pathogen detection; to achieve this, the distance between the sensor and magnetic labels must be minimized. 2) The nanobeads must be monodisperse, water soluble, chemically and magnetically stable, and functionalized to attach to a DNA fragment; the nanobeads should also be superparamagnetic so that they will not agglomerate in the absence of applied fields. 3) The bio-magnetic DNA microarrays need to be designed to maximise the active sensing surface area.