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March 2022 - Solution
The solutions are 17923 for n = 5 and 1584269 for n = 7. Anders Kaseorg provided a more detailed list:
For n = 1, every p = 2, 3, 5, 7 has E[p] = 5/2 = 2.5.
For n = 2, best is p = 17 with E[p] = 89/21 = 4.238095238095238.
For n = 3, best is p = 179 with E[p] = 149/11 = 13.545454545454545.
For n = 4, best is p = 1237 with E[p] = 43997/1061 = 41.46748350612629.
For n = 5, best is p = 17923 with E[p] = 1016453/8363 = 121.5416716489298.
For n = 6, best is p = 124679 with E[p] = 13169147/34453 = 382.235131918846.
For n = 7, best is p = 1584269 with E[p] = 729641181/586081 = 1244.9493858357462.