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KNIGHT Challenge
Kidney clinical Notes and Imaging to Guide and Help personalize Treatment and biomarkers discovery

A new approach to benchmark the acceleration of scientific discovery for cancer biomarkers

  • About KNIGHT
  • The Challenge
  • Evaluation
  • Baseline
  • Organizers
  • ISBI Proceedings
  • Winners

Important Dates

Release of data, code, and metrics for training Nov. 15, 2021
Release of examples for submission files Jan. 21, 2022
Release of data and metrics for testing Jan. 31, 2022
Challenge workshop website goes live Feb. 01, 2022
Submission deadline for prediction results files Final Round 3 Feb. 28, 2022
Mar. 7 2022 23:59 PST
Manuscript submission deadline Mar. 16, 2022 23:59 PST
Mar. 20, 2022 23:59 PST
Notification of ISBI sub-proceedings acceptance Mar. 24, 2022
KNIGHT Workshop Mar. 28, 2022
Camera-ready submission to ISBI sub-proceedings Apr. 15, 2022
Publication of challenge outcomes Oct. 01, 2022

Like the KNIGHT Challenge?

Try the BRIGHT challenge for breast tumor images.

Baseline

We created a PyTorch-based code example (https://github.com/IBM/fuse-med-ml/tree/master/fuse_examples/classification/knight) that demonstrates a basic classification pipeline for the KNIGHT challenge Kidney Classification (KiC) dataset. We utilized the FuseMedML library for all stages in the pipeline including data preprocessing, feature extraction, network training and metrics calculation. The baseline implementation can be used as an end-to-end example and serve as a point of comparison for tasks 1 and 2. In this example, we extract features from the CT volumes using a 3D ResNet-18 backbone, concatenate them with available clinical features processed by a smaller fully connected network, and classify the combined features into two risk groups as defined in the 1st task of the KNIGHT challenge.

Here are the results on a validation set consisting of 20% of the 300 cases, when decoupling the imaging and clinical data, or using them together:

Clinical data only Imaging only Imaging + Clinical
0.87 0.71 0.85

As you can see, there is room to improve the contribution of imaging data to the overall results. We mention some of the limitations of this baseline implementation on the Github page.

The baseline uses FuseMedML, a Pytorch-based library. Participants who prefer to just use the popular Pytorch framework can easily obtain the already-prepared KNIGHT dataset and dataloader objects, from our baseline code and use raw Pytorch for everything else. The “knight_dataset” function in “baseline/dataset.py” creates and returns those items.

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