About cookies on this site Our websites require some cookies to function properly (required). In addition, other cookies may be used with your consent to analyze site usage, improve the user experience and for advertising. For more information, please review your options. By visiting our website, you agree to our processing of information as described in IBM’sprivacy statement. To provide a smooth navigation, your cookie preferences will be shared across the IBM web domains listed here.
Publication
Cancer Biochemistry Biophysics
Paper
Steric crowding and conformer stability of the diol-epoxides of benzo(c)phenanthrene
Abstract
The relative stabilities of conformers of the syn and anti-diastereomers of the fjord and bay-region diol-epoxides of benzo(c)phenanthrene (BCP) and benzo(a)anthracene (BA) have been calculated. Steric crowding in the fjord-region of BCP is shown to stabilize the syn-diequatorial and anti-diaxial conformers of BCP. In contrast, the most stable conformers of the bay-epoxides of BA are found to be the syn-diaxial and anti-diequatorial.