Point of interest (POI) recommendation, which provides personalized recommendation of places to mobile users, is an important task in location-based social networks (LBSNs). However, quite different from traditional interest-oriented merchandise recommendation, POI recommendation is more complex due to the timing effects: We need to examine whether the POI fits a user's availability. While there are some prior studies which included the temporal effect into POI recommendations, they overlooked the compatibility between time-varying popularity of POIs and regular availability of users, which we believe has a non-negligible impact on user decision-making. To this end, in this paper, we present a novel method which incorporates the degree of temporal matching between users and POIs into personalized POI recommendations. Specifically, we first profile the temporal popularity of POIs to show when a POI is popular for visit by mining the spatio-Temporal human mobility and POI category data. Secondly, we propose latent user regularities to characterize when a user is regularly available for exploring POIs, which is learned with a user-POI temporal matching function. Finally, results of extensive experiments with real-world POI check-in and human mobility data demonstrate that our proposed user-POI temporal matching method delivers substantial advantages over baseline models for POI recommendation tasks.