Erhan Bilal, Theodore Sakellaropoulos, et al.
Bioinformatics
We present the concept of a nanoelectromechanical device capable of controlling the position of DNA inside a nanopore with a single nucleotide accuracy. The device utilizes the interaction of discrete charges along the backbone of a DNA molecule with the electric field inside the nanopore. In analogy to solid state transistors in which a small voltage controls the current between two electrodes, a voltage strategically located inside the nanopore can control the translocation of a single DNA molecule between a cis and a trans reservoirs. We propose an immediate application of the device as a replacement of capillary electrophoresis in DNA sequencing. © 2007 American Institute of Physics.
Erhan Bilal, Theodore Sakellaropoulos, et al.
Bioinformatics
Kyle Ellrott, Alex Buchanan, et al.
Genome Biology
Haiyuan Yu, Ronald Jansen, et al.
Bioinformatics
Gustavo Stolovitzky, Emily S.C. Ching
Physics Letters, Section A: General, Atomic and Solid State Physics