The physical environment is becoming more and more saturated with computing and communication entities that interact among themselves, as well as with users: virtually everything will be enabled to source information and respond to appropriate stimuli. In this technology-rich scenario, real-world components interact with cyberspace via sensing, computing and communication elements, thus driving towards what is called the CyberPhysical World (CPW) convergence. Information flows from the physical to the cyber world, and vice-versa, adapting the converged world to human behavior and social dynamics. Indeed humans are at the center of this converged world since information about the context in which they operate is the key element to adapt the CPW applications and services. Alongside, a new wave of (human) social networks and structures are emerging as important drivers for the development of novel communication and computing paradigms. In this article we present some of the research issues, challenges and opportunities in the convergence between the cyber and physical worlds. This article is not a comprehensive survey of all aspects of the CPW convergence. Instead, it presents some exciting research challenges and opportunities identified by members of the journal's editorial board with a goal to stimulate new research activities in the emerging areas of CPW convergence. © 2010 Elsevier B.V. All rights reserved.