About cookies on this site Our websites require some cookies to function properly (required). In addition, other cookies may be used with your consent to analyze site usage, improve the user experience and for advertising. For more information, please review your options. By visiting our website, you agree to our processing of information as described in IBM’sprivacy statement. To provide a smooth navigation, your cookie preferences will be shared across the IBM web domains listed here.
Publication
MicroTAS 2013
Conference paper
A microfluidic architecture for efficient reagent integration, reagent release, and analyte detection in limited sample volume
Abstract
Biological assays generally employ interactions between analytes and specific reagents for detecting analytes in samples. The miniaturization and the integration of these assays on microfluidic devices enable rapid, multiplexed point-ofcare tests using small amounts of samples and reagents. Here, we introduce a new microfluidic architecture that is only 6 μL in volume with an array of 8 parallel reagent and detection channels. This architecture "protects" the detection area against filling artifacts using valves, flow splitters and junctions, high and low flow resistances, and a bypass channel.